Calcium channel blockers for acute traumatic brain injury

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Calcium channel blockers for acute traumatic brain injury.

BACKGROUND Acute traumatic brain injury is a major cause of death and disability. Calcium channel blockers have been used in an attempt to prevent cerebral vasospasm after injury, maintain blood flow to the brain and so prevent further damage. OBJECTIVES To estimate the effects of calcium channel blockers in patients with acute traumatic brain injury and in a subgroup of brain injury patients...

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Voltage-Gated Calcium Channel Antagonists and Traumatic Brain Injury

Traumatic brain injury (TBI) is a leading cause of death and disability in the United States. Despite more than 30 years of research, no pharmacological agents have been identified that improve neurological function following TBI. However, several lines of research described in this review provide support for further development of voltage gated calcium channel (VGCC) antagonists as potential t...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2003

ISSN: 1465-1858

DOI: 10.1002/14651858.cd000565